| Autor: |
Abbas Ali Menshed, Hasan R. Khudhur, Luma Hakem Ali |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nano Biomedicine and Engineering, Vol 12, Iss 2, Pp 178-183 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2150-5578 |
| DOI: |
10.5101/nbe.v12i2.p178-183 |
| Popis: |
Coronary artery disease (CAD) is a widespread kind of cardiovascular disease and is a usual reason of heart attacks, including stable and unstable angina pectoris and myocardial infarctions. We designed this study to examine a probable correlation Interleukin-10 (-1082G/A) and tumor necrosis factor-α (G-308A) gene polymorphism and the coronary artery disease in the Iraqi population. The subjects enrolled in this study were categorized into 2 groups: Group one (140 subjects of CAD), and group two (95 healthy controls). There was no significant correlation between A allele and A/A genotype of TNF-α G-308A, and coronary artery disease patients (p-value = 0.715 and p-value = 0.762 respectively), while there was important correlation between G allele and G/G genotype of IL-10 (G-1082A), and coronary artery disease patients (p-value = 0.005 and p-value = 0.039 respectively). This study indicates that IL-10 G-1082A and TNF-α G-308A gene polymorphism may be considered a risk reason for coronary artery disease in Iraqis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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