A rare case of advance goblet cell carcinoma and a narrative review

Autor: Young Min Cho, Oluseyi Abidoye, Jifeng Wang, Sheena Bhushan, Santiago J. Miyara, Sara Guevara, Ernesto P. Molmenti, Richard J. LoCicero, Jawad Ahmed Ilyas
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Current Problems in Cancer: Case Reports, Vol 7, Iss , Pp 100181- (2022)
Druh dokumentu: article
ISSN: 2666-6219
DOI: 10.1016/j.cpccr.2022.100181
Popis: Goblet cell carcinoma (GCC) is a rare tumor. The diagnosis, management, and classification of GCC are controversial. The North American Neuroendocrine Tumor Society (NANETS) and European Neuroendocrine Tumor Society (ENETS) recommend classifying and treating GCC's as adenocarcinomas. However, recent data shows that GCC has a different driver mutation and prognosis. Therefore, a new classification and strategy of treatment are necessary. We present a case report of advanced GCC and highlight the challenges regarding management recommendations due to the lack of consensus. We believe that this literature review will emphasize the need for multidisciplinary management and highlight the knowledge gap which impacts treatment decisions.
Databáze: Directory of Open Access Journals