| Autor: |
Sachiyuki Tsukada, MD, PhD, Motohiro Wakui, MD, Kenji Kurosaka, MD, Masayoshi Saito, MD, Masahiro Nishino, MD, Naoyuki Hirasawa, MD, PhD |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
JBJS Open Access, Vol 8, Iss 1 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2472-7245 |
| DOI: |
10.2106/JBJS.OA.22.00125 |
| Popis: |
Background:. This study was performed to examine the hypothesis that the rate of allogeneic blood transfusion in patients who did not predeposit an autologous blood transfusion before single-anesthetic bilateral total knee arthroplasty (TKA) would be noninferior to that in patients who did predeposit blood. Methods:. We assessed the number of allogeneic transfusions required in 338 patients undergoing single-anesthetic bilateral TKA with a preoperative hemoglobin level of ≥11.0 g/dL. All TKAs were performed by a single surgeon according to the same operative and postoperative protocol. All patients received a combination of intravenous and intra-articular tranexamic acid. Neither a pneumonic tourniquet nor a drain was used. The difference in the risk of allogeneic transfusion between patients without and with autologous blood predeposit was compared with a noninferiority margin of 10 percentage points. Results:. Allogeneic transfusion was required in 1 (0.5%) of 194 patients who predeposited autologous blood and 3 (2.1%) of 144 patients who did not predeposit blood. The difference in risk was −1.6 percentage points (95% confidence interval, −4.1 to 1.0 percentage points); the confidence interval did not include the noninferiority margin and included zero. Conclusions:. In single-anesthetic bilateral TKA, allogeneic transfusion requirements in patients who did not predeposit autologous blood were noninferior to those in patients who predeposited blood. Level of Evidence:. Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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