| Autor: |
Li-Peng Liu, Qing-Song Lin, Wen-Yu Yang, Xiao-Juan Chen, Fang Liu, Xia Chen, Yuan-Yuan Ren, Min Ruan, Yu-Mei Chen, Li Zhang, Yao Zou, Ye Guo, Xiao-Fan Zhu |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Antimicrobial Resistance and Infection Control, Vol 12, Iss 1, Pp 1-9 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2047-2994 |
| DOI: |
10.1186/s13756-023-01269-1 |
| Popis: |
Abstract Background Neutropenic children with hematological diseases were associated with higher morbidity of carbapenem-resistant enterobacteriaceae (CRE) blood-stream infection (BSI) or colonization. But it was still murky regarding clinical characteristics, antimicrobial susceptibility, and outcomes of CRE-BSI in these patients. We aimed to identify the potential risk factors for subsequent bacteremia and clinical outcome caused by CRE-BSI. Methods Between 2008 and 2020, 2,465 consecutive neutropenic children were enrolled. The incidence and characteristics of CRE-BSI were explored in CRE-colonizers versus non-colonizers. Survival analysis was performed and risk factors for CRE-BSI and 30-day mortality were evaluated. Results CRE-carriers were identified in 59/2465 (2.39%) neutropenic children and19/59 (32.2%) developed CRE-BSI, while 12/2406 (0.5%) of non-carriers developed CRE-BSI (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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