The association between index of nutritional quality and ulcerative colitis: A case–control study
Autor: | Farhad Vahid, Samaneh Rashvand, Mahya Sadeghi, Azita Hekmatdoost |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: | |
Zdroj: | Journal of Research in Medical Sciences, Vol 23, Iss 1, Pp 67-67 (2018) |
Druh dokumentu: | article |
ISSN: | 1735-1995 1735-7136 |
DOI: | 10.4103/jrms.JRMS_555_17 |
Popis: | Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Recent studies have shown that dietary factors play an important role in the development of UC. Index of Nutritional Quality (INQ) is a suitable method that analyzes quantitatively and qualitatively single foods, meals, and diets. The aim of this study was to determine the association between INQ and UC. Materials and Methods: Overall, 62 newly diagnosed cases with UC and 124 healthy age- and sex-matched controls were studied in a referral hospital in Tabriz, Iran. INQ scores were calculated based on information on the usual diet that was measured by a valid and reliable Food Frequency Questionnaire consisting of 168 food items. Logistic regression analysis adjusting for age, gender, body mass index, education, smoking, Helicobacter pylori, family history of UC, appendectomy, alcohol, and total energy intake was used to estimate multivariable odds ratios (ORs). Results: After controlling for several covariates, we found inverse associations between UC risk and INQs of Vitamin C (OR = 0.34 [0.16–0.73]) and folate (OR = 0.11 [0.01–0.99]). In crude model of analysis, cases had a higher intake of total energy, protein, carbohydrate, total fat, saturated fatty acid, monounsaturated fatty acid, polyunsaturated fatty acid, niacin, Vitamin B6, Vitamin B12, magnesium, zinc, copper, selenium, and iron compared to controls, whereas controls had higher intakes of Vitamin C, Vitamin D, folate, and biotin compared to cases. Conclusion: Our results indicate that enough consumption of Vitamin C and folate was associated with lower risk of UC. |
Databáze: | Directory of Open Access Journals |
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