Impact of lipid profiles on parenchymal hemorrhage and early outcome after mechanical thrombectomy

Autor: Jie Li, Ling Long, Heng Zhang, Junliu Zhang, Adilijiang Abulimiti, Nuerbiya Abulajiang, Qingbo Lu, Wei Yan, Thanh N. Nguyen, Xiaodong Cai
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Annals of Clinical and Translational Neurology, Vol 10, Iss 10, Pp 1714-1724 (2023)
Druh dokumentu: article
ISSN: 2328-9503
DOI: 10.1002/acn3.51861
Popis: Abstract Objective We aimed to investigate the association of lipid parameters with parenchymal hemorrhage (PH) and early neurological improvement (ENI) after mechanical thrombectomy (MT) in stroke patients. Methods We retrospectively analyzed consecutive patients who underwent MT between January 2019 and February 2022 at a tertiary stroke center. PH was diagnosed and classified as PH‐1 and PH‐2 according to the European Cooperative Acute Stroke Study definition. ENI was defined as a decrease in the National Institutes of Health Stroke Scale (NIHSS) score by ≥8 or an NIHSS score of ≤1 at 24 h after MT. Results Among 155 patients, PH occurred in 41 (26.5%) patients, and 34 (21.9%) patients achieved ENI. In multivariate analysis, lower triglyceride to high‐density lipoprotein cholesterol ratio (TG/HDL‐C) value (OR = 0.51; 95% CI 0.30–0.89; p = 0.017) and higher HDL‐C level (OR = 5.83; 95% CI 1.26–26.99; p = 0.024) were independently associated with PH. The combination of TG
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