Issues and concerns in the management of progressive allograft dysfunction: A narrative review
| Autor: | Urmila Anandh, Pradeep Deshpande |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Indian Journal of Transplantation, Vol 16, Iss 1, Pp 42-47 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2212-0017 2212-0025 |
| DOI: | 10.4103/ijot.ijot_114_20 |
| Popis: | Nephrologists taking care of dialysis patients are increasingly encountering patients returning to dialysis after a failed transplant. These patients have a different pathophysiology and their medical issues differ from transplant-naïve dialysis patients. Prolonged cumulative immunosuppression and long-term exposure to chronic kidney disease (CKD) pathology are major factors responsible for increased complications and mortality. Often, their CKD-related issues are managed suboptimally as the emphasis is mostly on endeavors related to protecting allograft function. Managing their immunosuppression and allograft-related symptomatology poses serious challenges. There is also a dilemma as to whether the failed allograft should be left in situ or not. Considerate and appropriate decisions are required when these kidney allograft failure patients are offered re-transplantation. This review aims to address the major issues faced by transplant nephrologists in managing patients with allograft failure. |
| Databáze: | Directory of Open Access Journals |
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