Cost-effectiveness of reflex laboratory-based cryptococcal antigen screening for the prevention and treatment of cryptococcal meningitis in Botswana [version 2; peer review: 2 approved]

Autor: Mark W. Tenforde, Charles Muthoga, Andrew Callaghan, Ponego Ponatshego, Julia Ngidi, Madisa Mine, Alexander Jordan, Tom Chiller, Bruce A. Larson, Joseph N. Jarvis
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Wellcome Open Research, Vol 4 (2020)
Druh dokumentu: article
ISSN: 2398-502X
68729634
DOI: 10.12688/wellcomeopenres.15464.2
Popis: Background: Cryptococcal antigen (CrAg) screening for antiretroviral therapy (ART)-naïve adults with advanced HIV/AIDS can reduce the incidence of cryptococcal meningitis (CM) and all-cause mortality. We modeled the cost-effectiveness of laboratory-based “reflex” CrAg screening for ART-naïve CrAg-positive patients with CD4
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