Efficacy of indirect intense pulsed light irradiation on meibomian gland dysfunction: a randomized controlled study

Autor: Yu Cheng, Wen-Jing Song, Mei-Ting Huang, Yuan Gao, Luo-Ying Xie, Ying-Si Li, Song-Lin Yang, Xiao-Ming Yan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Ophthalmology, Vol 17, Iss 11, Pp 2014-2022 (2024)
Druh dokumentu: article
ISSN: 2222-3959
2227-4898
DOI: 10.18240/ijo.2024.11.06
Popis: AIM: To investigate the efficacy and mechanisms of indirect intense pulsed light (IPL) irradiation on meibomian gland dysfunction (MGD). METHODS: A total of 60 MGD patients was included in this prospective randomized controlled trial. Patients were randomly assigned 1:1 into two groups (3-mm group and 10-mm group) in which IPL was applied at distances from the lower eyelid margin of 3 and 10 mm, respectively. Both groups received three times treatment with 3-week interval. Meibomian gland yield secretion score (MGYSS), standard patient evaluation of eye dryness (SPEED) questionnaire, tear break-up time (TBUT), corneal fluorescein staining (CFS), and in vivo confocal microscopy were performed at baseline and after every treatment. RESULTS: After three IPL treatments, both groups had significant improvement in MGYSS (both P
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