Molecular epidemiological characterization and health burden of thalassemia in Jiangxi Province, P. R. China.

Autor: Min Lin, Tian-Yu Zhong, Yi-Guo Chen, Jian-Zhong Wang, Jiao-Ren Wu, Fen Lin, Xin Tong, Hui-Tian Yang, Xiao-Mei Hu, Rong Hu, Xiao-Fen Zhan, Hui Yang, Zhao-Yun Luo, Wen-Yu Li, Li-Ye Yang
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: PLoS ONE, Vol 9, Iss 7, p e101505 (2014)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0101505
Popis: BACKGROUND: Thalassemia is the most common inherited disease in southern China. However, this disorder is usually ignored by Jiangxi provincial health system and government due to lack of epidemiological data. MATERIALS AND METHODS: A total of 9489 samples from Hakka Han and Gan-speaking Han in three geographical areas of Jiangxi Province were analyzed for both complete blood cell (CBC) count and reverse dot blot (RDB) gene chip for thalassemia. RESULTS: 1182 cases of suspected thalassemia carriers with microcytosis (MCV
Databáze: Directory of Open Access Journals