β-Casomorphin increases fat deposition in broiler chickens by modulating expression of lipid metabolism genes

Autor: W.H. Chang, A.J. Zheng, Z.M. Chen, S. Zhang, H.Y. Cai, G.H. Liu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Animal, Vol 13, Iss 4, Pp 777-783 (2019)
Druh dokumentu: article
ISSN: 1751-7311
17517311
DOI: 10.1017/S1751731118002197
Popis: β-Casomorphin is an opioid-like bioactive peptide derived from β-casein of milk that plays a crucial role in modulating animal’s feed intake, growth, nutrient utilization and immunity. However, the effect of β-casomorphin on lipid metabolism in chickens and its mechanism remain unclear. The aim of this study was to investigate the effects of β-casomorphin on fat deposition in broiler chickens and explore its mechanism of action. A total of 120 21-day-old Arbor Acres male broilers (747.94±8.85 g) was chosen and randomly divided into four groups with six replicates of five birds per replicate. Three groups of broilers were injected with 0.1, 0.5 or 1.0 mg/kg BW of β-casomorphin in 1 ml saline for 7 days, whereas the control group received 1 ml saline only. The results showed that subcutaneous administration of β-casomorphin to broiler chickens increased average daily gain, average daily feed intake and fat deposition, and decreased feed : gain ratio (P
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