| Autor: |
V. I. Sokolova, D. A. Sychev, E. I. Vasilieva, M. B. Babarina, L. I. Zavolovskaya |
| Jazyk: |
ruština |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Антибиотики и Химиотерапия, Vol 65, Iss 5-6, Pp 25-29 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
0235-2990 |
| DOI: |
10.37489/0235-2990-2020-65-5-6-25-29 |
| Popis: |
The article analyses the results of the study of 169 strains of microorganisms obtained from wound discharge from 132 patients with diabetes mellitus. Staphylococcus spp. bacteria held a leading place among Gram-positive pathogens. Gram-negative pathogens — Escherichia coli, Pseudomonas aeruginosa, etc. — were found less frequently. All isolated cultures were sensitive to levofloxacin and moxifloxacin, and only Acinetobacter spp. (n=2) remained intact (in vitro) after the use of levofloxacin. The intra-arterial route of administration of levofloxacin (500 mg/day) in combination with polyoxidonium (12 mg/day) through a port was used in 16 patients with diabetic foot. In all clinical cases, positive dynamics was noted: subsiding of the inflammatory process, cleansing of the wound from a purulent-necrotic substrate, and early epithelialization of the wound was observed in patients with diabetic foot. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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