Myostatin as a plausible biomarker for early stage of sarcopenic obesity

Autor: Chisaki Ishibashi, Kaori Nakanishi, Makoto Nishida, Haruki Shinomiya, Maki Shinzawa, Daisuke Kanayama, Ryohei Yamamoto, Takashi Kudo, Izumi Nagatomo, Keiko Yamauchi-Takihara
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-79534-5
Popis: Abstract Since sarcopenic obesity (SO) impacts negatively on our health, early detection of SO is essential. However, prevalence of SO in an apparently healthy population has not been well examined. This study aimed to elucidate the prevalence and related factors of SO in middle-aged women, and to investigate useful diagnostic criteria for SO. Body component analyses were conducted on 432 female Osaka University employees aged 30–59 during their health checkups. Healthy (H) and SO groups were defined using cutoff values of 5.7 kg/m2 for skeletal muscle mass index and 30% for percent body fat. Serum myostatin and insulin levels were additionally measured. Among 432 participants, the prevalence of SO was 6.3%. Grip strength (P
Databáze: Directory of Open Access Journals
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