Persistence of long-term insulin independence after islet transplantation and two subsequent pregnancies

Autor: Sarah Gondek, Mateusz Ogledzinski, William Lin, Kamila Milejczyk, Braden Juengel, Lisa Potter, Piotr J. Bachul, Lindsay Basto, Laurencia Perea, Ling-Jia Wang, Martin Tibudan, Zuzanna Witkowska, Rolf Barth, John Fung, Piotr Witkowski
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: European Journal of Translational and Clinical Medicine, Vol 6, Iss 1, Pp 9-13 (2023)
Druh dokumentu: article
ISSN: 2657-3148
2657-3156
Popis: Pregnancy increases metabolic demand for insulin and may lead to the exhaustion of intraportally transplanted islets and post-gestational hyperglycemia. To prevent these complications, we implemented preemptive insulin supplementation during two subsequent pregnancies in an insulin-independent islet transplant recipient. This strategy resulted in optimal blood glucose control during the pregnancies, the preservation of the optimal islet graft function and the postpartum maintenance of long-term insulin independence.
Databáze: Directory of Open Access Journals