Persistence of long-term insulin independence after islet transplantation and two subsequent pregnancies
Autor: | Sarah Gondek, Mateusz Ogledzinski, William Lin, Kamila Milejczyk, Braden Juengel, Lisa Potter, Piotr J. Bachul, Lindsay Basto, Laurencia Perea, Ling-Jia Wang, Martin Tibudan, Zuzanna Witkowska, Rolf Barth, John Fung, Piotr Witkowski |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | European Journal of Translational and Clinical Medicine, Vol 6, Iss 1, Pp 9-13 (2023) |
Druh dokumentu: | article |
ISSN: | 2657-3148 2657-3156 |
Popis: | Pregnancy increases metabolic demand for insulin and may lead to the exhaustion of intraportally transplanted islets and post-gestational hyperglycemia. To prevent these complications, we implemented preemptive insulin supplementation during two subsequent pregnancies in an insulin-independent islet transplant recipient. This strategy resulted in optimal blood glucose control during the pregnancies, the preservation of the optimal islet graft function and the postpartum maintenance of long-term insulin independence. |
Databáze: | Directory of Open Access Journals |
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