Comparison of five methods for oxacillin susceptibility testing of Staphylococcus aureus isolates from cystic fibrosis patients
| Autor: | Marcelo J. Mimica, Rozane L. Carvalho, Eitan N. Berezin, Neiva Damaceno, Hélio H. Caiaffa-Filho |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo, Vol 54, Iss 6, Pp 305-306 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1678-9946 0036-4665 |
| DOI: | 10.1590/S0036-46652012000600002 |
| Popis: | Methicillin-resistant Staphylococcus aureus (MRSA) are now a worldwide problem. Cystic fibrosis (CF) patients are commonly colonized and infected by MRSA. Accurate oxacillin susceptibility testing is mandatory for the adequate management of these patients. We performed a comparison of the accuracy of different tests in CF isolates, including methicillin-susceptible S. aureus and MRSA with different SCCmec types, and using the mecA gene as the gold-standard. The sensitivity and specificity of oxacillin disc, Etest, and oxacillin agar screening plate were 100%. Sensitivity of the cefoxitin disc was 85% and specificity was 100%. For clinically relevant isolates, laboratories may consider the use of a combination of two phenotypic methods. |
| Databáze: | Directory of Open Access Journals |
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