Application of glucocorticoids in patients with novel coronavirus infection: From bench to bedside

Autor:	Linwei Lu, Jianhua Huang, Xiaohong Deng, Xianjun Sun, Jingcheng Dong
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	glucocorticoids glucocorticoid receptor glucocorticoid resistance respiratory system covid-19 Other systems of medicine RZ201-999
Zdroj:	Traditional Medicine and Modern Medicine, Vol 3, Iss 4, Pp 255-268 (2020)
Druh dokumentu:	article
ISSN:	2575-9000 2575-9019 25759000
DOI:	10.1142/S257590002030009X
Popis:	Glucocorticoids (GCs) have potential anti-inflammatory and immunosuppressive effects. There is plenty of controversy about the application of glucocorticoids in the treatment of coronavirus disease 2019 (COVID-19). This paper briefly summarizes the mechanism of glucocorticoids and their receptors and clinical applications in COVID-19. Through reviewing the current literature, our aim is to have a deeper understanding of the mechanism of GCs and their clinical applications, so as to find possible ways to enhance their efficacy and reduce drug resistance or side effects.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ecb55a3e3f4f4cdf8cfff1b47fecfedc Zobrazit plný text záznamu View record in DOAJ