| Autor: |
Chiyo Yano, Tomotaka Kawayama, Takashi Kinoshita, Yoshihisa Tokunaga, Jun Sasaki, Yuki Sakazaki, Masanobu Matsuoka, Haruki Imaoka, Mamoru Nishiyama, Kazuko Matsunaga, Kyoji Furukawa, Tomoaki Hoshino |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Allergology International, Vol 70, Iss 2, Pp 201-207 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1323-8930 |
| DOI: |
10.1016/j.alit.2020.09.009 |
| Popis: |
Background: Obesity is a risk factor for severe and difficult-to-treat asthma. However, the impact of different physiques on long-term outcomes is poorly understood. We aimed to investigate the correlation between obesity and asthma-associated long-term mortality in Japanese adults. Methods: From the data on 3146 individuals with air pollution-related respiratory diseases in the Omuta City Air Pollution-Related Health Damage Cohort Program, 697 adult patients with asthma were analyzed. Hazard ratios for long-term all-cause and respiratory disease -related mortality were compared in patients with different physiques using the Cox proportional hazard models. The classification of physiques was based on the WHO obesity criteria. Results: Of the 697 patients, 439 died during the median observation period of 26.3 years. The number (% of total) of underweight, normal-weight, pre-obese, and obese class I–III individuals were 75 (10.8%), 459 (65.9%), 140 (20.1%), and 23 (3.3%), respectively. The Cox proportional hazard model (adjusted hazard ratio [95% confidence interval], P value) showed that pre-obese group had a significantly reduced risk for all-cause (0.65 [0.51 to 0.83], P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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