Autor: |
Brittany A. Elliott, Hsiang-Ting Ho, Srivathsan V. Ranganathan, Sweta Vangaveti, Olga Ilkayeva, Hala Abou Assi, Alex K. Choi, Paul F. Agris, Christopher L. Holley |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-019-11375-7 |
Popis: |
The post-transcriptional modification of mRNAs provides an additional layer to gene expression regulation. Here the authors show that 2′-O-methylation mediated by box C/D snoRNAs and fibrillarin can inhibit the translation of target mRNAs. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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