Screening for Microalbuminuria in HIV-Positive Children in Enugu

Autor: Ezeonwu Bertilla Uzoma, Okafor Henrietta Uchenna, Ikefuna Anthony Nnaemeka, Oguonu Tagbo
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: International Journal of Nephrology, Vol 2012 (2012)
Druh dokumentu: article
ISSN: 2090-214X
2090-2158
DOI: 10.1155/2012/805834
Popis: Background. Human immunodeficiency virus associated nephropathy (HIVAN) is a rapidly progressive chronic renal parenchymal disease that occurs in HIV-infected individuals and manifests commonly as proteinuria, which is preceded by microalbuminuria (MA). This clinical entity is defined as a spot urine albumin of 20–200 mg/L. Objectives. To determine the prevalence of microalbuminuria in HIV positive children in UNTH, Enugu and compare it with that of HIV-negative children. Methods. A total of 154 HIV positive children aged 18 months to 14 years and 154 HIV-negative children of corresponding attributes were screened for microalbuminuria, using Micral test II strip which has a sensitivity of 90–99%. Results. No child among the groups (HIV positive and negative) had microalbuminuria. Majority (96.0%) of HIV-positive children had nonadvanced HIV disease at the time of the study (𝑃=0.00). About 77.3% were using HAART (𝑃
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