Potential Role of Global Longitudinal Strain in Cardiac and Oncological Patients Undergoing Cardio-Oncology Rehabilitation (CORE)

Autor: Gianluigi Cuomo, Francesca Paola Iannone, Anna Di Lorenzo, Crescenzo Testa, Michele Ciccarelli, Elio Venturini, Arturo Cesaro, Mario Pacileo, Ercole Tagliamonte, Antonello D’Andrea, Carmine Vecchione, Carlo Vigorito, Francesco Giallauria
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinics and Practice, Vol 13, Iss 2, Pp 384-397 (2023)
Druh dokumentu: article
ISSN: 2039-7283
DOI: 10.3390/clinpract13020035
Popis: Although shown to be effective in improving survival and quality of life in patients with cancer, some treatments are well-known causes of cardiotoxicity, such as anthracyclines, monoclonal antibodies against human epidermal growth factor receptor 2 (HER2) and radiotherapy. To prevent cardiovascular disease (CVD) in patients living with cancer, cardiologists and oncologists promoted the development of cardio-oncology, an interdisciplinary field which aims to further improving life expectancy in these patients. Cardio-oncology rehabilitation (CORE), through correction of risk factors, prescription of drug therapies and structured exercise programs, tries to improve symptoms, quality of life, cardiorespiratory fitness (CRF) and survival in patients with cancer. Different imaging modalities can be used to evaluate the real effectiveness of exercise training on cardiac function. Among these, the global longitudinal strain (GLS) has recently aroused interest, thanks to its high sensitivity and specificity for cardiac dysfunction detection due to advanced ultrasound programs. This review summarizes the evidence on the usefulness of GLS in patients with cancer undergoing cardiac rehabilitation programs.
Databáze: Directory of Open Access Journals
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