Structural and functional features of asthma participants with fixed airway obstruction using CT imaging and 1D computational fluid dynamics: A feasibility study

Autor: Quoc Hung Nguyen, So Ri Kim, Kum Ju Chae, Gong Yong Jin, Sanghun Choi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Physiological Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2051-817X
DOI: 10.14814/phy2.15909
Popis: Abstract Asthma with fixed airway obstruction (FAO) is associated with significant morbidity and rapid decline in lung function, making its treatment challenging. Quantitative computed tomography (QCT) along with data postprocessing is a useful tool to obtain detailed information on airway structure, parenchymal function, and computational flow features. In this study, we aim to identify the structural and functional differences between asthma with and without FAO. The FAO group was defined by a ratio of forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC), FEV1/FVC
Databáze: Directory of Open Access Journals
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