Cerium-based nanoparticles for cancer photodynamic therapy

Autor: Hui Li, Min Wei, Xinyi Lv, Yanling Hu, Jinjun Shao, Xuejiao Song, Dongliang Yang, Wenjun Wang, Buhong Li, Xiaochen Dong
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Innovative Optical Health Sciences, Vol 15, Iss 06 (2022)
Druh dokumentu: article
ISSN: 17935458
1793-7205
1793-5458
DOI: 10.1142/S1793545822300099
Popis: Metal- and metal-oxide-based nanoparticles have been widely exploited in cancer photodynamic therapy (PDT). Among these materials, cerium-based nanoparticles have drawn extensive attention due to their superior biosafety and distinctive physicochemical properties, especially the reversible transition between the valence states of Ce(III) and Ce(IV). In this review, the recent advances in the use of cerium-based nanoparticles as novel photosensitizers for cancer PDT are discussed, and the activation mechanisms for electron transfer to generate singlet oxygen are presented. In addition, the types of cerium-based nanoparticles used for PDT of cancer are summarized. Finally, the challenges and prospects of clinical translations of cerium-based nanoparticles are briefly addressed.
Databáze: Directory of Open Access Journals
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