Neurodevelopmental outcomes of very low birth weight preterms in preschool childhood: a prospective cohort study

Autor: Nadia Battajon, Chiara Bechini, Federica De Osti, Anna Galletti, Anna Chiara Frigo, Paola Lago
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Italian Journal of Pediatrics, Vol 49, Iss 1, Pp 1-9 (2023)
Druh dokumentu: article
ISSN: 1824-7288
DOI: 10.1186/s13052-023-01467-y
Popis: Abstract Background Preterm birth is a risk factor for a child’s neurological development. Preterm children have unusual neurodevelopmental profiles with executive, visual-motor functions, fine and gross motor skills, language and behavior that affect learning. In this study, we analyzed the neurodevelopmental outcomes of a cohort of very low birth weight infants admitted to the Treviso Neonatal Intensive Care Unit (NICU) between 2014 and 2016 and followed up to preschool childhood. Method This is a prospective cohort study. Infants were followed at birth and after NICU discharge at two- and four-year follow-ups. The two-year assessment was conducted with Bayley III, and at four years with the Wechsler Preschool and Primary Scale of Intelligence - III scales and Movement Assessment Battery for Children − 2. Results The cohort consisted of 207 subjects with a mean gestational age of 28.9 weeks, and a mean birth weight of 1097.2 g. At two years of age, children without disabilities were 90 (59.6%), those with minor disabilities 47 (31.1%), and those with major disabilities 14 (9.3%); at four years, 58.4% of children without previous disabilities, presented problems with verbal tests and manual dexterity: aiming, grasping and balance at movement assessment. There was significant alteration in processing speed (p
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