Autor: |
Nasrollah Rezaei-Ghaleh, Mehriar Amininasab, Sathish Kumar, Jochen Walter, Markus Zweckstetter |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/ncomms11359 |
Popis: |
Protein aggregation plays a crucial role in several neurodegenerative diseases. Here the authors demonstrate that phosphorylation of β-amyloid aggregates—the pathological hallmark of Alzheimer's disease—can change the molecular properties of aggregates, suggesting how phosphorylation contributes to disease progression. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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