In Vitro Destruction of Pathogenic Bacterial Biofilms by Bactericidal Metallic Nanoparticles via Laser-Induced Forward Transfer

Autor: Alena Nastulyavichus, Eteri Tolordava, Andrey Rudenko, Darya Zazymkina, Pavel Shakhov, Nikolay Busleev, Yulia Romanova, Andrey Ionin, Sergey Kudryashov
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nanomaterials, Vol 10, Iss 11, p 2259 (2020)
Druh dokumentu: article
ISSN: 2079-4991
DOI: 10.3390/nano10112259
Popis: A novel, successful method of bactericidal treatment of pathogenic bacterial biofilms in vitro by laser-induced forward transfer of metallic nanoparticles from a polyethylene terephthalate polymeric substrate was suggested. Transferred nanoparticles were characterized by scanning and transmission electron microscopy, energy-dispersive X-ray and Raman spectroscopy. The antibacterial modality of the method was tested on Gram-positive (Staphylococcus aureus) and Gram-negative (Pseudomonas Aeruginosa) bacterial biofilms in vitro, revealing their complete destruction. The proposed simple, cost-effective and potentially mobile biofilm treatment method demonstrated its high and broad bactericidal efficiency.
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