The influence of hay steaming on clinical signs and airway immune response in severe asthmatic horses

Autor: Marie Orard, Erika Hue, Anne Couroucé, Céline Bizon-Mercier, Marie-Pierre Toquet, Meriel Moore-Colyer, Laurent Couëtil, Stéphane Pronost, Romain Paillot, Magali Demoor, Eric A. Richard
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: BMC Veterinary Research, Vol 14, Iss 1, Pp 1-11 (2018)
Druh dokumentu: article
ISSN: 1746-6148
DOI: 10.1186/s12917-018-1636-4
Popis: Abstract Background Avoidance of antigenic stimuli was found to significantly reverse airway obstruction of horses with severe equine asthma (sEA). To date, no published study investigated the influence of steaming hay on lower airway condition of sEA-affected horses. The objectives were to determine the clinical, cytological and cytokine respiratory responses of both sEA and control (CTL) horses experimentally exposed to steamed or dry hay. Results A cohort of 6 sEA horses and 6 CTL horses was involved in this field study. On day 0, both groups were fed with steamed hay for 5 consecutive days, followed by a wash-out period of 26 days prior to be fed with dry hay for 5 consecutive days. Investigations performed 2 days prior to and 5 days after each challenge included clinical score, tracheal mucus accumulation, and bronchoalveolar lavage fluid (BALF) cytology and cytokine mRNA expression. Feeding steamed hay significantly decreased its mould content (P
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