Remission and relapse in granulomatosis with polyangiitis in a young womAn
| Autor: | Madalina-Pusa Duna, Lucia Radu, Constantin-Ioan Busuioc, Cristina Iosif, Narcis Copca, Denisa Predeteanu |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Romanian Journal of Rheumatology, Vol 29, Iss 2, Pp 92-95 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1843-0791 2069-6086 |
| DOI: | 10.37897/RJR.2020.2.8 |
| Popis: | Granulomatosis with polyangiitis (GPA) is a rare disorder characterized by inflammation of small and medium-sized blood vessels (vasculitis) that results in damage to various organ systems of the body, most often the respiratory tract and kidneys. The relapse rate rises from about 20% at 12 months to about 60% at 5 years. The combination of glucocorticoids and cyclophosphamide remains the standard therapy for patients with generalised GPA. Nevertheless, some patients do not respond satisfactorily to this treatment. Here we present a 32 year-old female with relapsing GPA successfully treated with methotrexate for ear, nose and throat (ENT) manifestation. |
| Databáze: | Directory of Open Access Journals |
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