Biomarkers of Progressive Fibrosing Interstitial Lung Diseases
| Autor: | E. V. Bolotova, Yu. G. Yurkova |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2023 |
| Předmět: |
interstitial lung diseases
biomarkers laboratory diagnostics progressive fibrosing phenotype Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Diseases of the circulatory (Cardiovascular) system RC666-701 Surgery RD1-811 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 |
| Zdroj: | Инновационная медицина Кубани, Vol 0, Iss 4, Pp 126-133 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2541-9897 |
| DOI: | 10.35401/2541-9897-2023-8-4-126-133 |
| Popis: | Despite adequate therapy, interstitial lung diseases (ILD) can cause progressive scarring of lung tissue. This type of ILD is known as progressive fibrosing ILD (PF-ILD). The challenge in diagnosing PF-ILD lies in the lack of uniformly accepted criteria for a progressive fibrosing phenotype. Most authors use criteria based on clinical features and assessment of functional imaging and radiological findings over time. However, forced vital capacity (FVC) measurement is limited by its variability, and the followup lasts 12 years. The above diagnostic challenges prevent from prescribing early adequate therapy in patients with progressive ILD, indicting the need to search for new biomarkers of the progressive fibrosing phenotype. We review the most studied and informative biomarkers of fibrosis progression in patients with ILD. |
| Databáze: | Directory of Open Access Journals |
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