| Autor: |
Biagio Anderlini, Andrea Severini, Camilla Ferrari, Claudio Fontanesi, Vittorio Ascari, Niccolò Braidi, Fabrizio Roncaglia |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Applied Sciences, Vol 14, Iss 11, p 4357 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2076-3417 |
| DOI: |
10.3390/app14114357 |
| Popis: |
In this study, we demonstrate the direct preparation of dihalo-γ-lactams featuring two distinct halogens from dichloroamides using a novel atom exchange radical cyclization (AERC) procedure. This method integrates the established atom transfer radical cyclization (ATRC) with halogen exchange in solution. The technique operates under mild conditions and requires small amounts of metallic copper, serving as both a supplemental activator and reducing agent. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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