Apoptosis-Inducing Action of Antituberculosis Drugs of the Main Group in Vitro

Autor: O. A. Vasilyeva, V. A. Serebryakova, O. I. Urazova, V. V. Novitsky, T. E. Kononova, I. O. Naslednikova
Jazyk: ruština
Rok vydání: 2020
Předmět:
Zdroj: Антибиотики и Химиотерапия, Vol 55, Iss 11-12, Pp 25-29 (2020)
Druh dokumentu: article
ISSN: 0235-2990
Popis: The influence of the main antituberculosis drugs (isoniazid, rifampicin, ethambutol) on in vitro apoptosis of peripheral blood lymphocytes from patients with pulmonary tuberculosis was researched. It was shown that all the investigated drugs induced apoptotic death of the lymphocytes in vitro, that could result in disturbance of antigen-specific response formation in pulmonary tuberculosis.
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