Inflammatory Response to Acute Myocardial Infarction Complicated by Cardiogenic Shock
| Autor: | Radek Pudil, Jan Krejsek, Vladimír Pidrman, Jaroslav Gregor, Miloš Tichý, Jan Bureš |
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| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: | |
| Zdroj: | Acta Medica, Vol 44, Iss 4, Pp 149-151 (2001) |
| Druh dokumentu: | article |
| ISSN: | 18059694 1211-4286 1805-9694 |
| DOI: | 10.14712/18059694.2019.103 |
| Popis: | We report a case of a 60-year-old man with acute myocardial infarction (AMI) treated using thrombolysis, and complicated by cardiogenic shock (CS). Plasma interleukin (IL) 1β, IL 6, IL 8, tumor necrosis factor alpha (TNFα), and soluble adhesion molecule (sICAM 1, sE-selectin) levels were measured at 3-h intervals. This observation showed the effect of AMI and CS on the plasma interleukin levels. Remarkable changes were found in the plasma TNF α level, which reached two significant peaks. The peak of the first elevation caused by AMI (80.11 pg/ml, vs. normal value 4.35 pg/ml, SD 21.3 pg/ml) was seen 6 h after the onset of the symptoms. After the period of significant decrease, TNF α level was increasing until the end of the observation period because of CS (the last TNF α level was 204.1 pg/ml). The plasma IL 1β level was continually increased during the period of observation (maximal IL 1β level 32.1 pg/ml, normal value |
| Databáze: | Directory of Open Access Journals |
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