Autor: |
Y. E. Willems, A. deSteiguer, P. T. Tanksley, L. Vinnik, D. Fraemke, A. Okbay, D. Richter, G. G. Wagner, R. Hertwig, P. Koellinger, E. M. Tucker-Drob, K. P. Harden, Laurel Raffington |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024) |
Druh dokumentu: |
article |
ISSN: |
1868-7083 |
DOI: |
10.1186/s13148-024-01637-7 |
Popis: |
Abstract Self-control is a personality dimension that is associated with better physical health and a longer lifespan. Here, we examined (1) whether self-control is associated with buccal and saliva DNA-methylation (DNAm) measures of biological aging quantified in children, adolescents, and adults, and (2) whether biological aging measured in buccal DNAm is associated with self-reported health. Following preregistered analyses, we computed two DNAm measures of advanced biological age (principal-component PhenoAge and GrimAge Acceleration) and a DNAm measure of pace of aging (DunedinPACE) in buccal samples from the German Socioeconomic Panel Study (SOEP-G[ene], n = 1058, age range 0–72, M age = 42.65) and saliva samples from the Texas Twin Project (TTP, n = 1327, age range 8–20, M age = 13.50). We found that lower self-control was associated with advanced biological age in older adults (PhenoAge Acceleration β = − .34, [− .51, − .17], p |
Databáze: |
Directory of Open Access Journals |
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