Evaluation of the Influence of Sulfur-Fumigated Paeoniae Radix Alba on the Quality of Si Wu Tang by Chromatographic and Chemometric Analysis

Autor: Ke Pei, Hao Cai, Yu Duan, Feng-Xian Qiao, Si-Cong Tu, Xiao Liu, Xiao-Li Wang, Xiao-Qing Song, Kai-Lei Fan, Bao-Chang Cai
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Analytical Methods in Chemistry, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-8865
2090-8873
DOI: 10.1155/2016/8358609
Popis: An accurate and reliable method of high-performance liquid chromatographic fingerprint combining with multi-ingredient determination was developed and validated to evaluate the influence of sulfur-fumigated Paeoniae Radix Alba on the quality and chemical constituents of Si Wu Tang. Multivariate data analysis including hierarchical cluster analysis and principal component analysis, which integrated with high-performance liquid chromatographic fingerprint and multi-ingredient determination, was employed to evaluate Si Wu Tang in a more objective and scientific way. Interestingly, in this paper, a total of 37 and 36 peaks were marked as common peaks in ten batches of Si Wu Tang containing sun-dried Paeoniae Radix Alba and ten batches of Si Wu Tang containing sulfur-fumigated Paeoniae Radix Alba, respectively, which indicated the changed fingerprint profile of Si Wu Tang when containing sulfur-fumigated herb. Furthermore, the results of simultaneous determination for multiple ingredients showed that the contents of albiflorin and paeoniflorin decreased significantly (P
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