Factors Associated with the Abandonment of Tuberculosis Treatment in Brazil: A Systematic Review

Autor: Larissa Araújo de Lucena, Gabriela Bezerra da Silva Dantas, Taynara Vieira Carneiro, Hênio Godeiro Lacerda
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 56 (2023)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-0155-2022
Popis: ABSTRACT Background: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis. In Brazil, TB is a public health problem, and the treatment dropout rate contributes to it. Methods: This systematic review investigated the factors associated with TB treatment dropout in Brazil using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method. The databases used were Bireme, Scopus, PubMed, Medline, Pan-American Health Organization (PAHO), and Latin-American and Caribbean Literature on Health Sciences (LILACS). The search was conducted on May 16, 2021. Nine articles were reviewed, and all were published within the last 5 years in English, Spanish, or Portuguese. Results: The sample sizes in the studies ranged from 148 to 77,212 individuals, and the studies enrolled only adult patients (aged 18-59 years) in Brazil. Evidence suggests that the significant risk factors associated with TB treatment dropout are male sex, black race/ethnicity, age between 19 and 49 years, human immunodeficiency virus (HIV) co-infection, low education (
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