| Autor: |
Frank T Wieringa, Maiza Campos Ponce, Marinka van der Hoeven, Annika M Weber, Silvia Barbazza, Moretta D Fauzi, Asrinisa Rachmadewi, Ririh Zuhrina, Fildzah K Putri, Rimbawan Rimbawan, Zuraidah Nasution, Puspo E Giriwono, Damayanti D Soekarjo, Elizabeth P Ryan |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
BMJ Open, Vol 13, Iss 11 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2023-076805 |
| Popis: |
Introduction Current formulations of ready-to-use therapeutic foods (RUTFs) to treat severe acute malnutrition (SAM) in children focus on nutrient density and quantity. Less attention is given to foods targeting gut microbiota metabolism and mucosal barrier functions. Heat-stabilised rice bran contains essential nutrients, prebiotics, vitamins and unique phytochemicals that have demonstrated favourable bioactivity to modulate gut microbiota composition and mucosal immunity. This study seeks to examine the impact of RUTF with rice bran on the microbiota during SAM treatment, recovery and post-treatment growth outcomes in Jember, Indonesia. Findings are expected to provide insights into rice bran as a novel food ingredient to improve SAM treatment outcomes.Methods and analysis A total of 200 children aged 6–59 months with uncomplicated SAM (weight-for-height z-scores (WHZ) |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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