A comparison of rat degloving injury models

Autor: Serdar Altun, Hakan Orbay, Mehmet Ekinci, Ahmet Cetinbas, Ali Bal, Enver Arpaci, Mehmet İhsan Okur
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Acta Orthopaedica et Traumatologica Turcica, Vol 51, Iss 4, Pp 308-312 (2017)
Druh dokumentu: article
ISSN: 1017-995X
DOI: 10.1016/j.aott.2017.03.007
Popis: Objective: Two different rat models for degloving injury were described in the literature. Our aim in this study is to compare these rat models to determine which one is more reliable and reproducible. Methods: We surgically induced degloving injury on tails and left hindlimbs of Wistar albino rats (n = 8), and sutured the avulsed tissues back in their original positions after a waiting period. We observed the changes in the avulsed flaps every other day for 10 days. At the end of follow-up period we evaluated the lesions in avulsed flaps by macroscopic measurement of necrosis and histological ulcer scoring using the National Pressure Ulcer Advisory Panel (NPUAP) Scale. Results: The average length of necrosis in avulsed tail flaps was 28.42 ± 3.04 mm, whereas there was no necrosis in avulsed hindlimb flaps (p
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