| Autor: |
Maria Joaquina Vieira, Aderson de Farias Dias, Alfredo Mayall Simas, Joseph Miller, Petrônio Filgueiras de Athayde Filho, Bruno Freitas Lira |
| Jazyk: |
angličtina |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 7, Iss 11, Pp 791-800 (2002) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/71100791 |
| Popis: |
The title compounds were synthesized from C-aryl-N-methylglycines by Naroylation followed by a cyclodehydration to form the corresponding 1,3-oxazolium-5-olates. These were not isolated but converted to the title compounds by an in situ 1,3-dipolar cycloaddition/cycloreversion sequence using carbon disulphide. We have studied the cyclodehydration step using acetic anhydride, trifluoroacetic anhydride and 1,3-dicyclohexylcarbodiimide (DCC) at temperatures not exceding 60oC. Trifluroacetic anhydride proved to be the best reagent, giving a better yield and more easily purified products, although yields were also acceptable with the other two reagents. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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