The role of supporting services in driving SARS-CoV-2 transmission within healthcare settings: A multicenter seroprevalence study

Autor: Amal Al-Maani, Adil Al Wahaibi, Jabir Al-Sooti, Bader Al Abri, Intisar Al Shukri, Elham AlRisi, Laila Al Abri, Khalid AlDaghari, Mahmood Al Subhi, Salima AlMaqbali, Salim AlBurtamani, Asma AlAbri, Ahmed Al Salami, Iman Al-Beloushi, Najla Al-Zadjali, Abdullah Alqayoudhi, Hanan Al-Kindi, Khalifa Al Shaqsi, Amina Al-Jardani, Seif Al-Abri
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 107, Iss , Pp 257-263 (2021)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2021.04.071
Popis: Objective: To determine the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in healthcare workers (HCWs) based on risk of exposure to COVID-19 patients. Method: This was a SARS-CoV-2 seroprevalence cross-sectional study in risk-stratified HCWs randomly selected from three main district hospitals in Oman. Results: 1078 HCWs were included, with an overall SARS-CoV-2 seroprevalence of 21%. The seropositivity rates in low-, variable-, and high-risk groups were 29%, 18%, and 17%, respectively (p-value < 0.001). The study found higher positivity in males (crude odds ratio [COR] 1.71, 95% confidence interval [CI] 1.28–2.3), and workers residing in high-prevalence areas (COR 2.09, 95% CI 1.42–3.07). Compared with doctors, workers from supporting services, administration staff, and nurses were more likely to test positive for SARS-CoV-2 antibodies (COR 9.81, 95% CI 5.26–18.27; 2.37, 95% CI 1.23–4.58; 2.08 95% CI 1.14–3.81). The overall rate of previously undetected infection was 12%, with higher values in low-risk HCWs. High district prevalence was a driving factor for seropositivity in the low-risk group (adjusted odds ratio [AOR] 2.36, 95% CI 1.0–5.59). Conclusion: Low-risk supporting services workers can drive SARS-CoV-2 transmission in hospitals. More attention and innovation within this area will enhance the safety of health care during epidemics/pandemics.
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