| Autor: |
Eros Luiz de Sousa, Antônio Felipe Paulino de Figueiredo Wouk, Osvaldo Malafaia, Jurandir Marcondes Ribas-Filho, Lucia Noronha, Silvana Maris Cirio, Claudia Turra PimpãoVII, Carlos Hespanha Marinho Júnior, Maria Fernanda Torres, Yorgos Luiz Santos de Salles Graça, Daniel Dantas Ferrarin |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Acta Cirúrgica Brasileira, Vol 31, Iss 5, Pp 320-326 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
0102-8650 |
| DOI: |
10.1590/S0102-865020160050000005 |
| Popis: |
ABSTRACT PURPOSE : To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use. METHODS: Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period. Control group received only morphine during the same period. Each group was divided into three sub-groups of 7, which were euthanized at 5, 10, and 21 days postoperatively. Comparison was based in histological evaluation of collagen type I and III using sirius red, immunohistochemical through vascular endothelial growth factor and matrix metalloproteinase-9. RESULTS: Healing process in scheduled periods did not show significant differences (p>0.05) between the COX and control groups during any of the periods. CONCLUSION: The use of meloxicam in the postoperative period following ileal anastomosis did not affect healing. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
