Overcoming the Odds: Successful Treatment of Disseminated Mucormycosis with Gastrointestinal and Jaw Involvement in a Patient with Acute Myeloid Leukemia

Autor: Thuraya Al-Busaidi, Fatma Al-Bulushi, Adil Al-Zadjali, Abdulaziz Bakathir, Abdullah Balkhair, Ibrahim Al Busaidi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Case Reports in Infectious Diseases, Vol 2023 (2023)
Druh dokumentu: article
ISSN: 2090-6633
DOI: 10.1155/2023/5556540
Popis: Disseminated mucormycosis is a rare life-threatening fungal infection that is uniquely seen in severely immunocompromised patients including those with hematological malignancies. We report a case of disseminated mucormycosis with a biopsy-proven gastrointestinal and oral cavity involvement in a patient with acute myeloid leukemia during induction chemotherapy. The patient had a successful outcome with limited resection of the involvement bowel segment, multiple maxillary dental extractions, debridement of the alveolus and hard palate, and combined antifungal therapy. After clinical improvement, stable infection on serial abdominal imaging, and completion of 6 weeks of combined antifungal therapy, consolidation chemotherapy was given, and molecular remission was achieved. The patient remained clinically well on secondary antifungal prophylaxis.
Databáze: Directory of Open Access Journals
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