Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis

Autor: Paola Barboro, Alessandra Rubagotti, Paola Orecchia, Bruno Spina, Mauro Truini, Erica Repaci, Giorgio Carmignani, Andrea Romagnoli, Carlo Introini, Francesco Boccardo, Barbara Carnemolla, Cecilia Balbi
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Cellular Oncology, Vol 30, Iss 1, Pp 13-26 (2008)
Druh dokumentu: article
ISSN: 1570-5870
1875-8606
DOI: 10.1155/2008/686940
Popis: Introduction: Although several molecular markers for bladder cancer have been identified, at present little information on prognostic biomarkers is available in the literature. Prognostication of this tumor is largely based on clinicopathological characteristics. Our aim was to identify nuclear matrix (NM) proteins that might serve to better characterize the phenotype of the invasive bladder cancer and to investigate their diagnostic and prognostic roles.
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