Development of myasthenia gravis in a patient with chronic myeloid leukemia during treatment with nilotinib

Autor:	David Sanford, Maria MacDonald, Michael Nicolle, Anargyros Xenocostas
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	chronic myeloid leukemia tyrosine kinase inhibitors adverse drug events Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Hematology Reports, Vol 6, Iss 2 (2014)
Druh dokumentu:	article
ISSN:	2038-8322 2038-8330
DOI:	10.4081/hr.2014.5288
Popis:	We report on a patient diagnosed with chronic myeloid leukemia (CML) who developed myasthenia gravis while on treatment with nilotinib. Autoimmune disease, including the development of myasthenia gravis, has been described in association with CML as well as the use of tyrosine kinase inhibitors. Second generation tyrosine kinase inhibitors are highly effective in the treatment of CML, although can result in adverse effects related to off-target kinase inhibition, and longer term reporting of adverse effects is required.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/b3faf4565b8640dda6f64fb8daf7174d Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF