The use of 4.5% hypertonic saline challenge test in diagnosing asthma in children with chronic recurrent cough
| Autor: | Bambang Supriyatno, Dina Medina, Alan R Tumbelaka, Nastiti N Rahajoe |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Paediatrica Indonesiana, Vol 45, Iss 3, Pp 93-8 (2016) |
| Druh dokumentu: | article |
| ISSN: | 0030-9311 2338-476X |
| DOI: | 10.14238/pi45.3.2005.93-8 |
| Popis: | Background The 4.5% hypertonic saline (HS) challenge test has several benefits compared to histamine challenge test as gold stan- dard. Saline is an inexpensive non-pharmacological substance which is relatively safe. Its mechanism in inducing bronchospasm resembles that of asthma. Moreover, it can easily be made in a modest medical laboratory. Objective To determine the ability of 4.5% HS challenge test com- pared to histamine challenge test in diagnosing asthma in children with chronic recurrent cough (CRC). Methods This study was a diagnostic test on children with CRC aged 6 to 14 years, conducted in outpatient clinic of Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta. All subjects underwent lung function tests. Subjects whose FEV 1 was |
| Databáze: | Directory of Open Access Journals |
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