Drug correction of intestinal dyskinesias

Autor: M. A. Butov, E. M. Shurpo, P. S. Kuznetsov, I. A. Zagravskaya
Jazyk: ruština
Rok vydání: 2016
Předmět:
Zdroj: Медицинский совет, Vol 0, Iss 14, Pp 96-99 (2016)
Druh dokumentu: article
ISSN: 2079-701X
2658-5790
DOI: 10.21518/2079-701X-2016-14-96-99
Popis: Selective myotropic spasmolytics are the most effective modern correction means for pain at irritable bowel syndrome. Currently various drugs of mebeverine hydrochloride are represented in the domestic market, the dosage of the active substance in which is identical but they are produced by various technologies. We established that in patients with the irritable bowel syndrome administration of the drug Niaspam (Sun Pharmaceutical Industries Ltd.) at standard dosages for 2 weeks showed high effectiveness in arresting pain syndrome and intestinal dyskinesias. Niaspam statistically reliably reduces the relative intensity of intestinal contractions, normalizes the contraction rythmicity but effective predominantly in lower parts of the gastrointestinal tract. Peculiarities of the production technology allow gradual mebeverine release from the capsule, which is extremely important in therapy of intestinal dyskinesias.
Databáze: Directory of Open Access Journals