Nanoparticles as carriers of proteins, peptides and other therapeutic molecules

Autor: Pudlarz Agnieszka, Szemraj Janusz
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Open Life Sciences, Vol 13, Iss 1, Pp 285-298 (2018)
Druh dokumentu: article
ISSN: 2391-5412
DOI: 10.1515/biol-2018-0035
Popis: Nanoparticles have many applications both in industry and medicine. Depending upon their physical and chemical properties, they can be used as carriers of therapeutic molecules or as therapeutics. Nanoparticles are made of synthetic or natural polymers, lipids or metals. Their use allows for faster transport to the place of action, thus prolonging its presence in the body and limiting side effects. In addition, the use of such a drug delivery system protects the drug from rapid disintegration and elimination from the body. In recent years, the use of proteins and peptides as therapeutic molecules has grown significantly. Unfortunately, proteins are subject to enzymatic digestion and can cause unwanted immune response beyond therapeutic action. The use of drug carriers can minimize undesirable side effects and reduce the dose of medication needed to achieve the therapeutic effect. The current study presents the use of several selected drug delivery systems for the delivery of proteins, peptides and other therapeutic molecules.
Databáze: Directory of Open Access Journals