Cervical human papillomavirus infection and persistence: a clinic-based study in the countryside from South Brazil

Autor: Janaina Coser, Thaís da Rocha Boeira, Jonas Michel Wolf, Kamila Cerbaro, Daniel Simon, Vagner Ricardo Lunge
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Brazilian Journal of Infectious Diseases, Vol 20, Iss 1, Pp 61-68 (2016)
Druh dokumentu: article
ISSN: 1413-8670
DOI: 10.1016/j.bjid.2015.10.008
Popis: Human papillomavirus (HPV) infection is common in sexually active women and viral persistence may cause intraepithelial lesions and eventually progress to cervical cancer (CC). The present study aimed to investigate epidemiological factors related to HPV infection and to evaluate viral persistence and CC precursor lesions frequencies in women from a city in the countryside of South Brazil. Three hundred women were recruited from a primary public health care clinic. The patients were interviewed and underwent sampling with cervical brushes for HPV-DNA detection/typing by a PCR-based assay and cytological analysis by Pap smear test. HPV was detected in 47 (15.7%) women. HPV infection was significantly associated with young age (
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