Early-stage hypertension defined by the 2017 ACC/AHA blood pressure guideline carries excessive cardiovascular risk in axial spondyloarthritis patients

Autor: Lin-Hong Shi, Ho So, Steven Ho Man Lam, Tena K. Li, Edmund Li, Cheuk-Chun Szeto, Lai-Shan Tam
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Therapeutic Advances in Musculoskeletal Disease, Vol 16 (2024)
Druh dokumentu: article
ISSN: 1759-7218
1759720X
DOI: 10.1177/1759720X241303314
Popis: Background: Hypertension (HTN) is the most important modifiable risk factor for the development of cardiovascular events (CVEs). Patients with axSpA are also associated with an increased risk of future CVE. Objectives: To ascertain whether baseline early-stage HTN is a predictor of future CVE in addition to inflammation in patients with axial spondyloarthritis (axSpA). Design: A retrospective cohort study. Methods: Patients with axSpA were recruited from 2001 to 2017. Patients with at least 2 years of follow-up and without prior CVE were divided into three groups according to the calculated mean blood pressure (BP) over the first 2-year follow-up period (adjusted mean BP) (⩾140/90, 130–139/80–89, and
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