Linking asymmetric cell division, CD8+ T cell fate, and signal strength

Autor: Jyoti Pokharel, Carmen Gerlach
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cell Reports, Vol 42, Iss 5, Pp 112548- (2023)
Druh dokumentu: article
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2023.112548
Popis: Through live imaging of CD8+ T cells carrying a fate reporter, Gräbnitz et al. directly linked (a)symmetric division to T cell fate.1 Asymmetry during the first division ensured the generation of stem-like CD8+ T cells following strong T cell stimulation.
Databáze: Directory of Open Access Journals