Evaluation of plasma prealbumin as a novel inflammatory biomarker in dogs: a pilot study
| Autor: | Sin-Wook Park, Keon Kim, Ock-Kyu Kim, Woong-Bin Ro, Chang-Min Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Frontiers in Veterinary Science, Vol 10 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2297-1769 94621896 |
| DOI: | 10.3389/fvets.2023.1142535 |
| Popis: | IntroductionPrealbumin (PAB) is a plasma protein synthesized in the hepatic parenchymal cells. PAB has a short half-life (~2 days), and its concentration is affected by changes in transcapillary escape. Measurement of PAB is widely used in hospitalized patients in human medicine due to its decreasing concentration in states of inflammation and malnutrition. However, only a few studies are available in dogs. The aim of this study is to determine whether the plasma PAB concentration decreases in dogs with inflammation and to evaluate the relationship between the plasma PAB concentration and inflammation-related parameters in dogs.MethodsA total of 94 dogs were divided into healthy (n = 33) and diseased (n = 61) groups. These were further divided into group A (n = 24) and group B (n = 37) according to plasma C-reactive protein (CRP) levels. Group A included dogs with a plasma CRP 0.05). A plasma PAB |
| Databáze: | Directory of Open Access Journals |
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