Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications

Autor: Tibiriçá Eduardo, Rodrigues Elba, Cobas Roberta, Gomes Marilia B
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Diabetology & Metabolic Syndrome, Vol 1, Iss 1, p 24 (2009)
Druh dokumentu: article
ISSN: 1758-5996
DOI: 10.1186/1758-5996-1-24
Popis: Abstract The present study was designed to study skin capillary density and recruitment of the upper and lower extremities in patients with type 1 diabetes with vascular complications, when compared to patients without complications and healthy subjects. We used intravital video-microscopy to measure basal and maximal (during venous congestion) skin capillary densities as well as capillary recruitment using post-occlusive reactive hyperemia (PORH) in the dorsum of the fingers and toes. Our results showed that besides microvascular vasodilation and loss of autoregulatory capacity, patients with type 1 diabetes with vascular complications present increased skin capillary density in both extremities.
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